Associate Professor Brett Langley

Recent Publications

• Shen, S., Picci, C., Ustinova, K., Benoy, V., Kutil, Z., Zhang, G., . . . Kozikowski, A. P. (2021). Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model. Journal of Medicinal Chemistry. doi:10.1021/acs.jmedchem.0c02210

• Picci, C., Wong, V. S. C., Costa, C. J., McKinnon, M. C., Goldberg, D. C., Swift, M., . . . Langley, B. (2020). HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice. Experimental Neurology, 328. doi:10.1016/j.expneurol.2020.113281

• Kalinski, A. L., Kar, A. N., Craver, J., Tosolini, A. P., Sleigh, J. N., Lee, S. J., . . . Twiss, J. L. (2019). Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. The Journal of Cell Biology, jcb.201702187. doi:10.1083/jcb.201702187

• Wong, V. S. C., Picci, C., Swift, M., Levinson, M., Willis, D., & Langley, B. (2018). α-Tubulin acetyltransferase is a novel target mediating neurite growth inhibitory effects of ‎chondroitin sulfate proteoglycans and myelin-associated glycoprotein‎. eNeuro, 5(1). doi:10.1523/ENEURO.0240-17.2018

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